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Mulert, Christoph; Lemieux, Louis:

Physiological Basis, Technique, and Applications

Preis:   197,94 Euro

Auflage: 1. Aufl.
Verlag: Springer-Verlag Berlin Heidelberg
Erscheinungsdatum: 11/2009
Seiten: 539 S.

ISBN-10: 3-540-87918-8   
ISBN-13: 978-3-540-87918-3

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Functional magnetic resonance imaging (fMRI) and Electronecephalography (EEG) are very important and complementary modalities since fMRI offers high spatial resolution and EEG is a direct measurement of neuronal activity with high temporal resolution. Interest in the integration of both types of data is growing rapidly as it promises to provide important new insights into human brain activity as it has already done so in the field of epilepsy. The availability of good quality instrumentation capable of providing interference-free data in both modalities means that electrophysiological and haemodynamic characteristics of individual brain events can be captured for the first time. Consequently, it seems certain that the integration of fMRI and EEG will play an increasing role in neuroscience and of the clinical study of brain disorders such as epilepsy.
The proposed book will discuss in detail the physiological principles, practical aspects of measurement, artefact reduction and analysis and also applications of the integration of fMRI and EEG. All applications, which are mainly in the fields of sleep research, cognitive neuroscience and clinical use in neurology and psychiatry will be reviewed.
General Physiology: The BOLD fMRI contrast mechansim.- Physiological Basis of the EEG.- Neurophysiological investigation of the basis of the fMNRI signal.- Fundamental Questions Concerning the Combination of EEG and fMRI:Simultaneous versus separate measurement of EEG and fMRI.- Comparison between EEG-based results and fMRI.- Acquisition and Preprocessing of Simultaneous EEG and fMRI: Feasibility and safety of simultaneous EEG/fMRI measurements.- Correction of gradient artefacts.- Corrections of cardioballistic artefacts.- Statistical Procedures and Models: Single trial coupling of EEG and fMRI.- Hemodynamic correlates of EEG: a heuristic.- Applications: The BOLD-response and frequency bands.-Vigilance.- Sleep research.- Investigation of the auditory system.- Investigation of the visual system.- Pain.- Epilepsy.- Applications in psychiatry.- Investigation of Cognitive Functions.- Simultaneous measurement of EEG and fMRI in the monkey.- Simultaneous EEG and fMRI at high fields.- High frequency oscillations and fMRI.