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Dallenbach-Hellweg, Gisela; Knebel Doeberitz, Magnus von; Trunk, Marcus J.:

Color Atlas of Histopathology of the Cervix Uteri
 
Preis:   197,94 Euro

Auflage: 2nd ed. Softcover version of original hardcover edition 2006
Verlag: Springer-Verlag Berlin Heidelberg
Erscheinungsdatum: 02/2010
Seiten: 196 S.

ISBN-10: 3-642-06433-7   
ISBN-13: 978-3-642-06433-3

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Beschreibung
The second edition of this atlas provides a detailed histopathological diagnosis of cervical disease emphasizing carcinogenesis, and correlating morphologic changes with clinical aspects. Instructions of how to obtain and handle tissue samples are followed by a description of the normal histology, of the action of steroid hormones on the cervix, and of the various forms of regeneration and inflammation. The section on etiology and pathogenesis of HPV-induced neoplasia has been enlarged to explain new insights into cellular and nuclear deregulation at the molecular level. A chapter on immunohistochemistry has been added which includes refined detection methods, e.g., with p16 for the early differential diagnosis of premalignant lesions. The latest advances in molecular biological research, with predictive subdivision of neoplasias, facilitate the choice of the proper therapy. All chapters ? supported by over 20 new microphotographs ? have been revised to include advances in the interpretation and management of cervical disease. The tumor nomenclature is adapted to the new WHO classification; the ICD-O code has been added. The reference list is updated with relevant publications.
Inhalt
Screening for Cervical Cancer Precursors to Prevent Invasive Disease.- Methods of Obtaining and Preparing Cervical Tissue for Histological Examination. "Diagnostic or Therapeutic Procedures"."Preparation of the Cervical Specimen".- Immunohistochemistry and In-Situ Hybridization. "Immunohistochemistry". - Normal Histology, Regeneration, and Repair. "Normal Ectocervix"."Ascending Repair"."Normal Endocervix"."Descending Repair"."Transformation Zone".- Vestigial and Heterotopic Tissues. "Mesonephric Duct Remnants and Hyperplasia"."Müllerian Duct Remnants and Metaplasia"."Heterotopic Ectodermal and Mesodermal Structures".- Hormonally Induced Changes. "Effects of Estrogen"."Effects of Endogenous Progesterone Under Hypersecretion"."Glandular Papillary Ectropium"."Polyps of the Ecto- and Endocervix."- Inflammatory Lesions.- "Nonspecific Ecto- and Endocervicitis"."Specific Inflammations"."Irradiation Changes"."Postoperative Spindle Cell Nodule". - Benign Tumors. "Epithelial Tumors"."Mesenchymal Tumors"."Mixed Tumors".- Premalignant Lesions. "Introduction"."Etiology and Pathogenesis."."Histopathology and Immunohistochemistry". - Malignant Tumors. "Epithelial Tumors"."Mesenchymal Tumors"."Mixed Epithelial And Mesenchymal Tumors"."Miscellaneous tumors"."Secondary Tumors".