Bücher für Medizin, Wissenschaft und Studium

Allgemeinmedizin
Biochemie
Genetik
Molekularbiologie

Metabolic pathways used to be ‘road maps’ most biologists learnt as undergraduates and then promptly forgot. Recent work has revealed how changes in metabolism are closely linked to many aspects of cell behavior and the development of cancer and other diseases. This book represents both a new look at metabolism and a refresher course. It surveys the major metabolic pathways, places these in biological context, and highlights the key control points that control cell behavior and can become dysregulated in disease.

Contents

(preliminary)

Foreword by Craig Thompson

Preface

1 Introduction to Metabolism
2 Metabolism Basics
3 Glycolysis: Reactions and Regulation
4 Mitochondria
5 NADPH
6 Carbohydrate Metabolism (Glycogen Storage and Gluconeogenesis)
7 Fatty Acid Oxidation and Synthesis
8 Amino Acid Degradation (Urea Cycle) and Amino Acid Synthesis
9 Nucleotide Synthesis and Degradation
10 Metabolic Demands of Proliferating Cells
11 Metabolism and Signaling
12 Future: Metabolism Regulates Cell and Molecular Biology

Appendix: Metabolomics by Ralph Deberardinis

Index

Genetics and Genome Science; Molecular Biology; Biochemistry; Medical Science